We have a vibrant team at Queen Mary University of London and a number of key collaborators around the world. We take a strongly multidisciplinary approach to our research, as you will see from team members.
Queen Mary team
Hazel Screen is a Professor in Biomedical Engineering at QMUL, with a first degree in Mechanical Engineering, and an MRes in Instrumentation Systems. Since completing her PhD in tendon mechanics in 2003, she had maintained focus in this area, and now leads a research group with particular interests in natural structure-function behaviour in soft tissues and understanding injury mechanisms.
Outside of work, she loves the great outdoors and spends a lot of time hiking and running. She is also a keen scuba diver, and loves to travel.
LinkedIn: Hazel Screen
Dr Dylan Morrissey is consultant physiotherapist at Bart's Health NHS Trust and an NIHR/HEE Senior Clinical Lecturer. He has published ~70 papers, and gained ~£3.5m research funding, on the link between movement and pathology. He has a particular focus on tendinopathy.
Dr Wing Keung Cheung (Tony)
Dr Wing Keung Cheung (Tony) joined Professor Hazel Screen's Group as a PDRA on an HBLB funded project to develop imaging tools to investigate tendon mechanics in horses.
Daniel Rowson has an MA and MEng in Engineering for the Life Sciences from the University of Cambridge and is currently in the third year of his PhD. He is investigating the response of the primary cilia to stress deprivation in tendon explants. He is also investigating cilia response to loading in vitro. Ideally he aims to discover the primary mechanism controlling cilia length in tendon and discover what effect cilia length has on cell response and whether this plays a role in tendinopathy. As well as science Dan likes cooking, eating and the board game go/baduk.
Colm Daly is a physiotherapist who worked in elite sport for seven years before completing his MSc in Sports and Exercise Medicine in QML in 2012. He has since commenced his PhD studies exploring the persistent biomechanical factors associated with prior hamstring injury. He combines research with clinical and teaching roles. His research focus is to identify biomechanical features (muscle activity and movement characteristics) associated with prior hamstring injury. The key impact of this research is to develop screening strategies for hamstring re-injury prevention.
Paulina Kloskowska is an energetic, highly motivated and highly skilled sports physiotherapist. She has completed both B.Sc. and M.Sc. in Physiotherapy in Poland, after that she has moved to London to start her PhD investigating the biomechanics of groin pain. She is particularly interested in lower limb injuries, rehabilitation and biomechanics. Her educational activity involves giving lectures to intercalated BCs Sports Medicine students in Anatomy, Biomechanics and Rehabilitation as well as supervising BSc and MSc students’ projects. Her overarching career aim and ambition is to further develop and refine clinical while incorporating academic work to ensure her treatment strategies are always based on the latest evidence. Most of all, she wishes to contribute to medical science in areas that require further research and development.
Marta Godinho has a BSc in Bioengineering and a MSc in Biomedical Engineering and has undertaken various projects in the biomaterials area. She is currently in the third year of her PhD investigating the role of elastin in tendon function. Marta is a very optimistic person, with a good sense of humour. In her spare time, she enjoys walking, skiing, traveling and cooking.
Renjie Liu has completed his undergraduate study in Polymer Science at Donghua University. He received a scholarship from China Scholarship Council and is currently a second year PhD student at QMUL. His project involves developing a novel type of biomaterial with gecko feet adhesive properties to aid tendon repairs. His interests are music and electronics.
Sarah Morton is a doctor who completed her intercalated BSc in Sports and Exercise Medicine four years ago. Since then she has continued her project work and has also been involved in organising SEM lectures and seminars for students in London.
Amit Chauhan is a 4th year medical student at Bart’s & The London who achieved a first class honours in his intercalated BSc in Sports & Exercise Medicine last year. He has had the opportunity to carry out innovative research on the risk factors for Achilles tendinopathy alongside professionals who are world-leading pioneers in that field. Amit is also the President and Co-Founder of The London Sports & Exercise Medicine Society (LSEMS), a regional society promoting the field of SEM to all undergraduate medical and physiotherapy students across London.
Hatim Abdulhussein is a 4th year medical student at Barts’ and the London. A graduate from the Sports and Exercise Medicine BSc at the CSEM, Queen Mary, University of London, he has carried out some exciting research on HVIGI’s, looking at the injections mechanism of action and the role of the steroid in its treatment effect. Hatim is currently Chair and Co-Founder of The London Sports and Exercise Medicine Society (LSEMS), a regional society promoting the field of SEM to all undergraduate medical and physiotherapy students across London.
Dr Saira Chaudhry is a Posdoctoral teaching fellow at WHIR, QMUL. Her research focuses on investigating and developing techniques to understand the multi-scale mechanics and structure of connective tissues particularly tendons. Her interest incorporates in vivo human models to in vitro animal models. She is also a fellow of HEI.
Florence is a specialist registrar in Sports and Exercise Medicine on the academic training pathway, having recently started the first of her academic rotations at the Mile End site. She graduated from UCL with MBBS in 2008 having completed an intercalated BSc in physiology in 2005. She is currently undertaking an MSc in Sports Medicine, Exercise and Health.
Florence is at present focusing on comparing clinical, imaging and histopathological features of Achilles tendinopathy in athletes and patients with systemic inflammatory conditions.
Victoria is a London GP, has a special interest in musculoskeletal conditions and is a member of the Faculty of Sports and Exercise Medicine. She is a PhD fellow (with a focus on musculoskeletal education of GPs) at Queen Mary, University of London, where she also teaches undergraduate and postgraduate students in Sports and Exercise Medicine. Victoria sits on RCGP Council, the North Central and East London Local Education and Training Board Council and is a board member of the NHS Tower Hamlets Clinical Commissioning Group.
Dr Stephanie Bryant
Professor Peter Clegg
Professor Peter Clegg is Professor of Musculoskeletal Biology at the University of Liverpool. He is a qualified veterinary surgeon, who maintains his speciality in equine surgery. He heads a research group which has a major interest in tendon biology, particularly relating to structure-function relationship in tendon and ligaments in both the veterinary species and in man. His group also has a strong interest in articular biology, particularly relating to chondrocyte cell biology and cartilage turnover.
Professor Helen Birch
Professor Helen Birch's research interests are in skeletal tissues, particularly tendons and ligaments, and their dynamic nature. Her research team is interested in the immediate dynamic response to an applied load (mechanical properties) and the dynamic response over the longer term (tissue turnover), which occurs during adaptation and ageing. The team focuses primarily on the extracellular matrix, in particular the protein collagen, from a molecular level to the gross structure. The extracellular matrix is responsible for the immediate dynamic response of tendons, differs between tendons with different functional requirements (energy storing and positional tendons) and changes during ageing and in disease. Understanding the extracellular matrix in skeletal tissues is therefore fundamental to understanding the functioning of these complex structures in health and disease.
Graham Riley's primary research interest is the molecular pathology of soft connective tissues such as tendon and ligament. These tissues are common sites of injury, often affected by long-term pain and prone to rupture, even in non-athletic individuals. His research team uses techniques of cell and molecular biology, histology, immunohistochemistry and biochemistry. His team collaborate with clinicians and surgeons at the Norfolk and Norwich Hospital, in particular the Institute of Orthopaedics, to obtain human tissue samples for analysis
Martin Knight's research is focussed on 'mechanobiology' or how living cells and tissues respond to physical forces. In particular, he is interested in the mechanical properties of cells and the role of the fascinating cellular structure the primary cilium. Studies from his group were the first to show that primary cilia were required for cartilage mechanotransduction and he has also discovered that cilia are involved in fundamental pathological signalling processes. He is collaborating with Dr Hazel Screen's group to investigate the role of primary cilia associated signalling in tendinopathy. He also has a strong interest in promoting the public understanding of science. Outside work he enjoys the 'great outdoors', exploring wilderness areas with his family. He is interested in wildlife and environmental issues, and has tried his hand at creative ceramics and fly fishing!
Chavaunne Thorpe is an Arthritis Research UK Career Development Fellow with a keen interest in tendon structure-function relationships. She graduated with a 1st class degree in Equine Science from the University of Bristol, and subsequently completed a PhD in Tendon Matrix Biology at UCL. She joined QMUL as a post doctoral research associate, working on a project funded by the Horserace Betting Levy Board to investigate the initiation and progression of tendinopathy in racehorses. During this project, she discovered the importance of the interfascicular matrix in tendon function, which led to further funding from the BBSRC to characterise the role of the interfascicular matrix in tendon health and ageing. She left QMUL in November 2016 to take up a fellowship position at the Royal Veterinary College, funded by Arthritis Research UK. During her fellowship, she will be investigating the role of the tendon progenitor cell population in tendon homeostasis, injury and repair. In her spare time, she enjoys riding her horse Betsy, running and cooking.
Dr Damae Zamboulis
Danae is a post-doctoral research assistant with an interest in musculoskeletal biology. She has a degree in Veterinary Medicine and an Equine Medicine and Surgery internship from the Aristotle University of Thessaloniki, Greece. She undertook a PhD at the University of Liverpool in equine laminitis and joined our group in 2016 as a post-doctoral research assistant. She is currently working on a joint University of Liverpool and QMUL project funded by the Horserace Betting Levy Board investigating the development of the interfascicular matrix in energy-storing tendons in horses. In her spare time, Danae enjoys playing and coaching rugby and staying active.
Ewa Spiesz has a wide experience in bioengineering including Biomaterials (MSc), Biomechanics (PhD) and Biophysics (postdoc), with a focus on collagenous tissues structure-function relationships at multiple scales. Her training lies predominantly in relating the physical behaviour of tissues (tendon and bone) with the underlying biology and/or physiology using experimental and computational methods. Techniques applied involve mechanical testing, nanoindentation, atomic force microscopy, quantitative backscattered electron imaging (qBEI), quantitative polarized light microscopy (qPLM) and micro computed tomography, as well as micromechanical homogenization, finite element and statistical mechanical simulations.
Charlie Waugh is a postdoctoral researcher whose research interests broadly include muscle and tendon physiology and mechanics in relation to movement performance. She read Veterinary Sciences at the Royal Veterinary College, London, giving her a broad physiological background, before completing a PhD in musculoskeletal biomechanics at Brunel University. This has proven advantageous in relation to viewing her research with a holistic approach, and in identifying fundamental questions relating to the mechanisms underpinning normal and pathological musculoskeletal structure and function. Charlie joined QML as a post-doctoral researcher in 2011, where she investigated the biological response of healthy and pathological tendons to extracorporeal shockwave therapy, a treatment intervention used in Sports Medicine for treating degenerative tendinopathies
Peter Malliaras is a physiotherapist specializing in tendinopathy management and rehabilitation, consulting at Complete Sports Care (Hawthorn, Melbourne) and a research fellow at La Trobe University (Australia) and Queen Mary, University of London (UK). He completed his PhD in 2006, identifying novel risk factors for tendinopathy among athletes, and has since co-authored over 45 peer review tendinopathy publications. He spent five years in the UK undertaking post-doctoral research focusing on tendinopathy imaging and rehabilitation, and consulting to the general public and elite athletes with difficult and non-responsive lower limb tendinopathy. He has been consulted in the rehabilitation of elite football, rugby, netball, volleyball, basketball, track and field, skating and cricket athletes, as well as the Royal Ballet (London). Prior to consultant work, Peter worked at the Victorian Institute of Sport, toured nationally and internationally with football, track and field, volleyball, basketball and weight lifting, and has been an official team physiotherapist at a Commonwealth Games meet.
Henning Langberg is Professor at the Institute of Public Health at University of Copenhagen, Denmark. He has published more than 135 scientific articles in peer-reviewed journals listed in PubMed as well as a long list of book chapters in the area of sports physical therapy, basic science and related areas. At present Henning Langberg is one of the worlds leading researcher on the adaptation of human tendons to exercise and loading (from basic science to clinical guidelines for tendinopathy treatment). He has served in many international and national scientific and professional organizations including as a board member for the International Federation of Sports Medicine (2001-2009). He is recipient of several international and national awards including the Research Award of the International Federation of Sports Physiotherapy. Henning Langberg is a highly used lecturer at national and international conferences and has plus 100 lectures and keynotes presentations within the area of sports medicine. He is a clinical specialist in sports physiotherapy announced by the Danish Physiotherapy association.
Alex Scott is a graduate of the UBC Physical Therapy program, and the UBC Experimental Medicine PhD program. His research targets a widespread problem, overuse injuries and chronically painful tendon disorder in workers and athletes. Dr Scott is the lead investigator on an international, multicenter randomized controlled clinical trial investigating the efficacy of platelet rich plasma (PRP) in combination with exercise for patellar tendinopathy. He is a coinvestigator on a local randomized controlled trial examining intramuscular stimulation (a form of acupuncture therapy) as a treatment for Achilles tendinopathy. His laboratory is examining the basic biology of tendon responses to mechanical loading and/or injury. His research has been highlighted and supported locally by organizations including the WorksafeBC, Professional Association of BC and the Health Sciences Association, nationally through CIHR sponsored events and seminars, and internationally including sponsorship by the Canada-Scandinavia Foundation and the Swedish Research Council. He maintains active collaborations with Oslo University, Umeå University, and University of Paris. His work has been incorporated into a widely used web-based clinical guideline (UpToDate©).
Dr Steve Greenwald
Steve Greenwald is professor of cardiovascular mechanics in the Blizard Institute at Barts & The London School of Medicine & Dentistry. His first degree in Chemistry (Hertford College, Oxford) was followed by a PhD in Medicine at Guy’s Hospital Medical School. His research interests include the relationship between structure and function in elastic tissues, mechanical factors in the pathogenesis of cardiovascular disease and the development of non-invasive methods for measuring cardiovascular performance. When not working he spends his time dabbling in DIY, transport and industrial history, food, wine and, more wholesomely, in cycling and skiing.
Past Team members
Jenny Shepherd is a post-doctoral researcher with an interest in the injury and regeneration of biological tissues and the role biomaterials can play in repair. She completed a MEng in Materials Science at the University of Oxford, before a PhD in the production of ceramic scaffolds for bone repair at the University of Cambridge. In her early post-doctoral career she moved to the application of synthetic collagen structures in the repair of load-bearing soft tissues such as tendons. Attempting to replicate the structure of these tissues led to a desire to investigate the natural tissues further and she joined QML as part of a Wellcome Trust Project considering the mechanics and biology of developing tendinopathy. The project investigated the initiation of micro-damage as a result of in vitro fatigue loading and the effect this had on tendon extension mechanisms, local strains & cell deformation. She has recently left QML, returning to the University of Cambridge to apply the experience gained to 3D engineered environments for regenerative medicine. In her spare time she enjoys travel, running, swimming, going to the gym and undoing all the good work by baking and eating out.
Liyong Jia finished his PhD in 2016 under the supervision of Professor Hazel Screen. He graduated in Clinic diagnosis from Southern Medical School in China and received a scholarship from China Scholarship Council to study at QMUL. His project involved characterising the mechanical behaviour of the aortic valves. His interests are swimming, running and badminton.
Dharmesh Patel is an early career researcher with a particular interest in tissue mechanics and mechanotransduction mechanisms. He has an IMechE accredited MEng degree in Medical Engineering from Queen Mary University of London, and completed a PhD under the supervision of Professor Hazel Screen where he investigated the effects of shear-tension ratios on Human Tenocyte metabolism using a novel fibre composite system. Dharmesh is currently working as a post-doctoral research assistant investigating the differences in structure and mechanics between energy storing and positional tendons, focusing on the interfascicular matrix, and how these properties change with age.
Chineye Princess Udeze has MEng in Medical Engineering during which she undertook a two months summer placement in Tissue Engineering for Tendon Mechanics, at QML. She has recently finished her PhD under the supervision of Professor Hazel Screen where she investigated the interdependence of perturbation frequency and magnitude on tenocyte metabolism and repair. Her research interests include tissue response to mechanical loading particularly in tendon, and mechanotransduction. As an undergraduate, she conducted research in tissue mechanics that tested two major hypotheses of tendon mechanics at the fascicular level. These included Tendon Micromechanics: Lateral Force Transmission between Fascicles (2011), and Tendon Mechanics Varies with Age (2012). In her spare time she enjoys swimming, travelling and going out with family and friends.
Roger Woledge was a visiting Professor at QMUL, where he worked closely with Dylan Morrissey and his students. Particular focus was given to project design, data analysis and post-graduate education. CW obtained his BSc in Physiology in 1959 at Universtity College London followed by research training with A.V.Hill 1959-62. He remained in UCL Physiology until his retirement in 2003, being Head of Dept (1988-1994) and Director of Institute of Human Performance in Stanmore (1994-2013). Since retirement he had continued his research work with many collaborators including the team at Queen Mary University London. His primary interest was muscle physiology (obituary).