Completed Projects

Previous funding has resulted in a wide range of key findings, advancing our knowledge in the tendon biomechanics or mechanobiology field. Details of these can be found here:

A comparison of clinical, imaging and histopathological characteristics of inflammatory and non-inflammatory tendinopathy

Super resolution (SIM) images of primary cilia in cultured cells. Primary cilia are stained in red (acetylated tubulin) the basal body is magenta (pericentrin) and actin is stained green (phalloidin).

The Role of the Primary Cilia in Tendinopathy

EPSRC

Tendinopathy: Treatment effects and mechanisms (Tendinopathy TEAM)

NIHR/HEE CAT Senior Clinical Lectureship scheme

The structural of the three layers of AVs

Strain transfer through the aortic valve and its relevance to the cellular mechanical environment

China Scholarship Council funded

A micro computed tomography scan of the interfascicular matrix in an equine tendon stained with sodium tungstate (white) with segmented collagen fibre bundles (transparent).

Role of interfascicular matrix in human tendons in relation to tendinopathy

Arthritis Research UK Funded: 20262

Musculoskeletal education for general practitioners

Fig 1: PEG-Peptide rod seeded with bovine tendon cells and stained with Calcein AM.

Human Tenocyte metabolism under pathological and physiological loading conditions

Arthritis Research UK Funded: NE/PhD/19598
National Institutes of Health USA Funded: R21

High Volume Image Guided Injections

Hamstring Associated Movement and Muscle activity deficits following Injury (HAMMI)

Confocal Image showing elastin organisation in the equine superficial digital flexor tendon. Longitudinal sections were immustained for elastin (red) and cell nuclei (blue).

Establishing the Role of Elastin in Tendon Function

Bonfield Scholarship - Institute of Bioengineering Queen Mary University of London

Designer polymer composite tapes for surgical tendon repair

Participant with sEMG electrodes and CodaMotion markers attached to his body during a single leg squat task.

Biomechanical correlates of long standing adduction related groin pain in professional and amateur athletes

Achilles and Patellar Tendinopathy Risk Factors

A biomechanical characterisation of eccentric (EL) and concentric loading (CL) of the triceps surae

Role of the inter-fascicular matrix in age related deterioration of tendon mechanical function

BBSRC Funded: BB/K008412 /1

Images of tenocytes attached to rods in the composites

Using hydrogels for novel tissue engineering applications

Leverhulme Trust Funded Visiting Research Professorship

A combined engineering and molecular approach to study the initiation and progression of tendinopathy

Arthritis Research UK Funded: MP 18424

Confocal image showing increased staining for MMP-3 (red) and MMP-13 (green) as a result of fatigue loading. Cell nuclei are stained blue

A Multidisciplinary investigation into the mechanics and biology of developing tendinopathy

Wellcome Trust

Mechanical loading (uniaxial) of tenocytes in 2D membranes or 3D collagen gels

The Role of High Frequency Loading In the Treatment of Tendinopathy

Orthopaedic Research UK Funded. OR UK 490

SEM image showing helix structure in an SDFT fascicle

Investigating aging in equine tendinopathy

Horse Race Betting Levy Board Funded: T23